A Seroepidemiological Investigation of Toxocariasis in Forestry Workers in Bulgaria

Authors

  • Eleonora Kaneva Department of Parasitology and Tropical Medicine, National Centre of Infectious and Parasitic Diseases, Bulgaria
  • Georgi Nikolov Department of Immunology, National Centre of Infectious and Parasitic Diseases, Bulgaria
  • Yana Kandova Laboratory Allergen Preparations, Bul Bio NCIPD
  • Bogdan Petrunov Department of Immunology, National Centre of Infectious and Parasitic Diseases, Bulgaria

DOI:

https://doi.org/10.7546/CRABS.2022.05.08

Keywords:

toxocariasis, seroprevalence, ELISA, Western blot, total IgE

Abstract

Determination of professional activities, which are connected with higher risk of toxocariasis, is very important for well-timed diagnosis and prevention. That is why our research aimed to investigate the spread of toxocariasis in people, whose professional activities are related with forests.

Thirty-three people are included in the study – eight employees of Forest Research Institute at Bulgarian Academy of Sciences, Sofia, and 25 forestry workers from three different locations in South Bulgaria.

The specific parasitological diagnosis of toxocariasis is performed with ELISA and Western blot. Presence of anti-Toxocara IgG antibodies in ELISA was established in eleven forestry workers. This reveals very high seroprevalence of toxocariasis among this profession – 33.3%. Moreover, the examination of 15 sera (11 with positive and 4 with borderline ELISA results for toxocariasis) with Western blot showed the presence of two and more antigen bands in 11 samples (33.3%). These results show that professional activities in the
forest could be defined as risk factor for development of toxocariasis. 

Author Biographies

Eleonora Kaneva, Department of Parasitology and Tropical Medicine, National Centre of Infectious and Parasitic Diseases, Bulgaria

Mailing Address:
Department of Parasitology
and Tropical Medicine,
National Centre of Infectious
and Parasitic Diseases
26 Yanko Sakazov Blvd
1504 Sofia, Bulgaria

E-mail: kaneva@ncipd.org

Georgi Nikolov, Department of Immunology, National Centre of Infectious and Parasitic Diseases, Bulgaria

Mailing Address:
Department of Immunology,
National Centre of Infectious
and Parasitic Diseases
26 Yanko Sakazov Blvd
1504 Sofia, Bulgaria

E-mail: labalerg@ncipd.org

Yana Kandova, Laboratory Allergen Preparations, Bul Bio NCIPD

Mailing Address:
Laboratory Allergen Preparations,
Bul Bio NCIPD
26 Yanko Sakazov Blvd
1504 Sofia, Bulgaria

E-mail: yanaka@abv.bg

Bogdan Petrunov, Department of Immunology, National Centre of Infectious and Parasitic Diseases, Bulgaria

Mailing Address:
Department of Immunology,
National Centre of Infectious
and Parasitic Diseases
26 Yanko Sakazov Blvd
1504 Sofia, Bulgaria

E-mail: petrunov@ncipd.org

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Published

31-05-2022

How to Cite

[1]
E. Kaneva, G. Nikolov, Y. Kandova, and B. Petrunov, “A Seroepidemiological Investigation of Toxocariasis in Forestry Workers in Bulgaria”, C. R. Acad. Bulg. Sci. , vol. 75, no. 5, pp. 686–693, May 2022.

Issue

Section

Biology