COVID-19-induced Kidney Injury – Analysis and Prognosis

Abstract

There is much data that the kidney may be a vulnerable organ in the cases with SARS-CoV-2 infection. Acute kidney injury (AKI) is the frequent and typical manifestation in COVID-19 associated with high mortality. In most cases the diagnosis AKI is identified by the higher values of the serum creatinine (sCr). A retrospective analysis of 120 positive patients, hospitalized in Military Medical Academy (MMA), Sofia in the period from October to December of 2021, has been conducted. The average age of the patients admitted for treatment with COVID-19 (69 male, 51 female) is 63.4 years, 70% of the patients have had accompanying diseases, 61% have been discharged from the hospital and 39% have died. The laboratory monitoring of the kidney indicators of all admitted patients shows that 34% had increased values of the serum creatinine while 44% had increased values of the blood urea nitrogen (BUN). The data from the urinal analysis show the presence of hematuria in 32% of the cases and proteinuria in 27.5% of the cases. A high frequency in the death cases had an AKI. Older age and comorbidities may aggravate the risk of renal injury in COVID-19 patients. The severe forms of COVID-19, forcing hospitalization, are often accompanied by a kidney dysfunction. AKI is a negative prognosis for survival in the cases of the infected by SARS-CoV-2.