The Effect of Low-Dose Ionizing Radiation (Computer Tomography) on the Functional Parameters of Male Gametes

Authors

  • Tsvetomira Dimitrova Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences and Invitro OB Gyn Medical Center “Dimitrov”, Bulgaria
  • Elena Hristova Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences
  • Vanyo Sharkov ”St. Anna” University Hospital, Bulgaria
  • Andrey Velichkov Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences
  • Plamen Todorov Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences and Invitro OB Gyn Medical Center “Dimitrov”, Bulgaria

DOI:

https://doi.org/10.7546/CRABS.2024.06.06

Keywords:

spermatozoa, low-dose ionizing radiation, motility, apoptosis

Abstract

Human semen (native and processed) was treated with different doses of ionizing radiation. The influence of the irradiation on motility, DNA fragmentation and level of apoptosis of spermatozoa has been investigated. The obtained results point out that the treatment of the samples with dosages usually used in medicinal diagnostics (computer tomography) does not have any effect on the total motility of the spermatozoa, but does influence certain specific kinetic parameters – amplitude of lateral head displacement (ALH) and beat/cros frequency (BCF). We did not observe any differences in the percentage DNA fragmentation between the experimental and the control groups. Irradiation with low-dose ionizing emissions increases the proportion of gametes in early apoptosis stage and the effect is dose-dependent.

Author Biographies

Tsvetomira Dimitrova, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences and Invitro OB Gyn Medical Center “Dimitrov”, Bulgaria

Mailing Addresses:
Institute of Biology and Immunology of Reproduction,
Bulgarian Academy of Sciences
73 Tsarigradsko Shosse Blvd
1113 Sofia, Bulgaria
and
Invitro OB Gyn Medical Center “Dimitrov”
2 Dr. Stoyan Chomakov St
1709 Sofia, Bulgaria

Email: tsvetomira_stz@abv.bg

Elena Hristova, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences

Mailing Address:
Institute of Biology and Immunology of Reproduction,
Bulgarian Academy of Sciences
73 Tsarigradsko Shosse Blvd
1113 Sofia, Bulgaria

Email: hristova.elena@gmail.com

Vanyo Sharkov, ”St. Anna” University Hospital, Bulgaria

Mailing Address:
”St. Anna” University Hospital
1 Dimitar Mollov St
1709 Sofia, Bulgaria

Email: kod_st_anna_sofia@abv.bg

Andrey Velichkov, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences

Mailing Address:
Institute of Biology and Immunology of Reproduction,
Bulgarian Academy of Sciences
73 Tsarigradsko Shosse Blvd
1113 Sofia, Bulgaria

Email: andreymb@abv.bg

Plamen Todorov, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences and Invitro OB Gyn Medical Center “Dimitrov”, Bulgaria

Mailing Addresses:
Institute of Biology and Immunology of Reproduction,
Bulgarian Academy of Sciences
73 Tsarigradsko Shosse Blvd
1113 Sofia, Bulgaria
and
Invitro OB Gyn Medical Center “Dimitrov”
2 Dr. Stoyan Chomakov St
1709 Sofia, Bulgaria

Email: plamen.ivf@gmail.com

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Published

30-06-2024

How to Cite

[1]
T. Dimitrova, E. Hristova, V. Sharkov, A. Velichkov, and P. Todorov, “The Effect of Low-Dose Ionizing Radiation (Computer Tomography) on the Functional Parameters of Male Gametes”, C. R. Acad. Bulg. Sci. , vol. 77, no. 6, pp. 831–838, Jun. 2024.

Issue

Section

Biology