Immunohistochemical Study of Female Breast Cancer in Varna, Bulgaria

Authors

  • Galina Yaneva Department of Biology, Faculty of Pharmacy, Medical University of Varna, Bulgaria
  • Ivan Maslarski Department of Anatomy and Histology, Pathology and Forensic Medicine, Faculty of Medicine, Sofia University “St. Kliment Ohridski”, Bulgaria

DOI:

https://doi.org/10.7546/CRABS.2024.01.07

Keywords:

female breast cancer, immunohistochemistry, molecular types

Abstract

An immunohistochemical study of 128 female breast cancer patients in Varna is performed. The expression of estrogen and progesterone receptors, human epidermal growth factor receptor 2 (HER2) and proliferation marker protein Ki-67 in terms of histological and molecular types and differentiation grade is assessed. Ductal carcinoma and luminal B HER2(+) prevail. The discrepancies between immunohistochemical positivity and negativity of single biomarkers are outlined.

Author Biographies

Galina Yaneva, Department of Biology, Faculty of Pharmacy, Medical University of Varna, Bulgaria

Mailing Address:
Department of Biology,
Faculty of Pharmacy,
Medical University of Varna
84 Tsar Osvoboditel Blvd, 9002 Varna, Bulgaria

E-mail: galina_yanevaa@abv.bg

Ivan Maslarski, Department of Anatomy and Histology, Pathology and Forensic Medicine, Faculty of Medicine, Sofia University “St. Kliment Ohridski”, Bulgaria

Mailing Address:
Department of Anatomy and Histology,
Pathology and Forensic Medicine,
Faculty of Medicine,
Sofia University “St. Kliment Ohridski”
1 Kozyak St, 1407 Sofia, Bulgaria

E-mail: maslarsky@gmail.com

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Published

29-01-2024

How to Cite

[1]
G. Yaneva and I. Maslarski, “Immunohistochemical Study of Female Breast Cancer in Varna, Bulgaria”, C. R. Acad. Bulg. Sci. , vol. 77, no. 1, pp. 55–61, Jan. 2024.

Issue

Section

Biology