An Endemic Species Nepeta phyllochlamys P. H. Davis: Composition of Essential Oil and Antimicrobial Activity of Extracts

Authors

  • Zeynep Gülcan Department of Pharmaceutical Botany, Faculty of Pharmacy, Anadolu University, Türkiye
  • Yavuz Bülent Köse Department of Pharmaceutical Botany, Faculty of Pharmacy, Anadolu University, Türkiye
  • Gökalp Işcan Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Türkiye
  • Mine Kürkçüoǧlu Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Türkiye

DOI:

https://doi.org/10.7546/CRABS.2024.01.04

Keywords:

Nepeta phyllochlamys, antimicrobial activity, essential oil, GC-FID, GC-MS

Abstract

This study investigates the composition of essential oil and biological activities of Nepeta phyllochlamys P. H. Davis, a local endemic species from the Lamiaceae family. Samples of N. phyllochlamys were collected from three populations, and essential oil components were compared among these populations. The main components identified in samples from three localities included caryophyllene oxide, δ-pinene, linalool, T-cadinol, α-pinene, and 14-nor-kadin-5-en-4-one (isomer A). Remarkably, the chemical content of the plant exhibited variations based on geographical regions. Although the plant showed limited antibacterial and anticandidal activities in tests, this research holds significant importance due to several factors. N. phyllochlamys is a local endemic species and part of the widely used Nepeta genus in traditional practices. Moreover, there is a scarcity of studies conducted on N. phyllochlamys, and to the best of our knowledge, no previous research has explored its phytochemical profile and antimicrobial properties. This article contributes valuable insights into the antimicrobial effects of N. phyllochlamys, shedding light on its chemical composition through the application of the GC-FID and GC-MS method.

Author Biographies

Zeynep Gülcan, Department of Pharmaceutical Botany, Faculty of Pharmacy, Anadolu University, Türkiye

Mailing Address:
Department of Pharmaceutical Botany,
Faculty of Pharmacy,
Anadolu University,
Eskişehir, Türkiye

E-mail: zgulcan@anadolu.edu.tr

Yavuz Bülent Köse, Department of Pharmaceutical Botany, Faculty of Pharmacy, Anadolu University, Türkiye

Mailing Address:
Department of Pharmaceutical Botany,
Faculty of Pharmacy,
Anadolu University,
Eskişehir, Türkiye

E-mail: ybkose@anadolu.edu.tr

Gökalp Işcan, Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Türkiye

Mailing Address:
Department of Pharmacognosy,
Faculty of Pharmacy,
Anadolu University,
Eskişehir, Türkiye

E-mail: giscan@anadolu.edu.tr

Mine Kürkçüoǧlu, Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Türkiye

Mailing Address:
Department of Pharmacognosy,
Faculty of Pharmacy,
Anadolu University,
Eskişehir, Türkiye

E-mail: mkurkcuo@anadolu.edu.tr

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Published

29-01-2024

How to Cite

[1]
Z. Gülcan, Y. Köse, G. Işcan, and M. Kürkçüoǧlu, “An Endemic Species Nepeta phyllochlamys P. H. Davis: Composition of Essential Oil and Antimicrobial Activity of Extracts”, C. R. Acad. Bulg. Sci. , vol. 77, no. 1, pp. 30–39, Jan. 2024.

Issue

Section

Chemistry