Assessment of the Subjectively Perceived Cognitive Deficit in Hospitalized Elderly Patients with Depression and the Relationship of Perceived Deficit Questionnaire – PDQ-D5 with the Socio-demographic and Clinical Factors

Authors

  • Jacklin Natzkova Department of Psychiatry, Medical University of Sofia, Bulgaria
  • Vessela Stoyanova Department of Psychiatry, Medical University of Sofia, Bulgaria

DOI:

https://doi.org/10.7546/CRABS.2023.02.14

Keywords:

late-life depression, cognition, PDQ-5D

Abstract

The aim of the current study was to assess subjective cognitive dysfunction in elderly depressed patients and the impact of socio-demographic and clinical factors on its presentation.

All patients aged ≥ 65 years, which were hospitalized in the Psychiatric Clinic of “Alexandrovska” University Hospital for a two-year period and met the ICD-10 criteria for depression, were included. They were evaluated by Hamilton Depression Rating Scale 24 items (HDRS24), its emotional-cognitive subscale (HDRScog) and its suicidal item (HDRSsuic), Geriatric Depression Scale 15 items (GDS15), its suicide subscale (GDSsuic), Perceived Deficit Questionnaire – Depression 5 items (PDQ-D5) and University of California, Los Angeles Loneliness Scale (UCLA-LS). The PDQ-D5, UCLA-LS and GDS15 were also applied to a control group of 50 healthy elderlies. The data were processed with the IBM SPSS Statistics 25.0.

Out of 131 patients, 29 had late-onset depression (LOD), 80 had recurrent depressive disorder (RDD) and 22 had bipolar depression (BD). Patients with BD had more episodes than those with RDD, and higher PDQ-D5 and HDRScog scores than those with LOD and RDD. The severity of PDQ-D5 correlated significantly with the severity of depression, loneliness, suicidal and HDRScog scores. After applying multiple linear regression analysis (R2 = 0.489, p <0.001) the UCLA-LS severity had the greatest impact on PDQ-D5, followed by HDRScog and depression severity, assessed by GDS15. The diagnosis of BD had
the least impact.

PDQ-D5 reflects the severity of the current late-life depression and correlates significantly with the loneliness, emotional-cognitive symptoms and self-assessment of depression.

Author Biographies

Jacklin Natzkova, Department of Psychiatry, Medical University of Sofia, Bulgaria

Mailing Address:
Department of Psychiatry,
Medical University of Sofia
1 St. Georgi Sofiiski St, 1431 Sofia, Bulgaria

E-mail: jacklin.natzkova@gmail.com

Vessela Stoyanova, Department of Psychiatry, Medical University of Sofia, Bulgaria

Mailing Address:
Department of Psychiatry,
Medical University of Sofia
1 St. Georgi Sofiiski St, 1431 Sofia, Bulgaria

E-mail: vestoyan@yahoo.com

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Published

26-02-2023

How to Cite

[1]
J. Natzkova and V. Stoyanova, “Assessment of the Subjectively Perceived Cognitive Deficit in Hospitalized Elderly Patients with Depression and the Relationship of Perceived Deficit Questionnaire – PDQ-D5 with the Socio-demographic and Clinical Factors”, C. R. Acad. Bulg. Sci. , vol. 76, no. 2, pp. 292–301, Feb. 2023.

Issue

Section

Medicine