Epilepsy and Mental Retardation in Children with Cerebral Palsy – Bulgarian Study

Authors

  • Elena Rodopska Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria
  • Nikolay Topalov Department of Neurology, Faculty of Medicine, Medical University of Sofia and Departement of Radiology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria
  • Iliana Aleksandrova Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria
  • Asya Asenova Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria
  • Daniela Deneva Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria
  • Maya Koleva Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria
  • Elena Slavkova Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria
  • Veneta Bojinova Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria

DOI:

https://doi.org/10.7546/CRABS.2022.12.18

Keywords:

cerebral palsy, epilepsy, mental retardation

Abstract

Epilepsy is common in children with cerebral palsy (CP). In a group of 521 children with cerebral palsy it was found that 58% (n = 303) of the affected had epilepsy and 74.5% (n = 388) had mental retardation. We found a
higher percentage of symptomatic epilepsy in a combination of CP with mental retardation – 84.2% (n = 255), while only 15.8% (n = 48) of children with normal intellect had epilepsy. In our CP patients, the focal seizures were the most common – 34.7% (n = 181), followed by the secondary generalized 29.6% (n = 154) and the generalized seizures (tonic, clonic and generalized tonicclonic) 25.3% (n = 132), most often with early onset, with 43.5% (n = 132) of them with onset in the first year of life. The earlier onset of the epileptic seizures correlated with a more severe mental retardation. We found that symptomatic epilepsy and severe mental retardation are most common in children with spastic quadriparesis.

Author Biographies

Elena Rodopska, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

E-mail: erodopska3007@yahoo.com

Nikolay Topalov, Department of Neurology, Faculty of Medicine, Medical University of Sofia and Departement of Radiology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria

Mailing Address:
Department of Neurology,
Faculty of Medicine,
Medical University of Sofia
1 St. Georgi Sofiiski St
1431, Sofia, Bulgaria

and

Departement of Radiology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

E-mail: nikolatbg@yahoo.com

Iliana Aleksandrova, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

and

Department of Neurology,
Faculty of Medicine,
Medical University of Sofia
1 St. Georgi Sofiiski St
1431, Sofia, Bulgaria

E-mail: iliyana_@abv.bg

Asya Asenova, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

and

Department of Neurology,
Faculty of Medicine,
Medical University of Sofia
1 St. Georgi Sofiiski St
1431, Sofia, Bulgaria

E-mail: as_asenova@mail.bg

Daniela Deneva, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

E-mail: dani_deneva@abv.bg

Maya Koleva, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

E-mail: maya8410@abv.bg

Elena Slavkova, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum”, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

E-mail: elenaslavkova@yahoo.com

Veneta Bojinova, Clinic of Child Neurology, University Hospital for Active Treatment in Neurology and Psychiatry “St. Naum” and Department of Neurology, Faculty of Medicine, Medical University of Sofia, Bulgaria

Mailing Address:
Clinic of Child Neurology,
University Hospital for Active Treatment
in Neurology and Psychiatry “St. Naum”
1 Dr. Lyuben Rusev St
1113, Sofia, Bulgaria

and

Department of Neurology,
Faculty of Medicine,
Medical University of Sofia
1 St. Georgi Sofiiski St
1431, Sofia, Bulgaria

E-mail: vsbojinova@abv.bg

Downloads

Published

23-12-2022

How to Cite

[1]
E. Rodopska, “Epilepsy and Mental Retardation in Children with Cerebral Palsy – Bulgarian Study”, C. R. Acad. Bulg. Sci. , vol. 75, no. 12, pp. 1852–1858, Dec. 2022.

Issue

Vol. 75 No. 12 (2022)

Section

Medicine

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