Analysis of Cell Proliferation and Apoptosis in Virtual Model
Keywords:apoptosis, breast cancer, cancer cell death rate, cancer cell repair rate, cell proliferation, chemotherapeutic agent
Breast cancer is the second leading cause of cancer among women globally. Several treatments are involved in breast cancer like surgery, chemotherapy, radiotherapy, and hormone therapy; chemotherapy being used most often. Multicellular systems complications can be deeply understood by analyzing and studying how cells grow, move, divide, die and interact. To examine these factors, we use PhysiCell as our modelling platform. Virtual cell growth analysis is essential to view the cancer cell growth daily. PhysiCell physics-based multicellular simulator is an open-source agent-based simulator used to design a virtual model to analyze the changing cell cycle progression, volume, death, motility, mechanics and processes. Analysis was made on the cancer cell death rate, cell damage rate, and cell repair rate. Data were taken for every 6 hours of simulation and the result confirms that the chemotherapeutic agent kills 45% of cancer cells.
How to Cite
LicenseCopyright (c) 2022 Proceedings of the Bulgarian Academy of Sciences
Copyright (c) 2022 Proceedings of the Bulgarian Academy of Sciences
Copyright is subject to the protection of the Bulgarian Copyright and Associated Rights Act. The copyright holder of all articles on this site is Proceedings of the Bulgarian Academy of Sciences. If you want to reuse any part of the content, please, contact us.