The Effect of Smoking on the Morphology of Lung Cancer

Authors

  • Iva Popova Medical Centre St. Kozma and St. Damyan, Bulgaria
  • Atanas Zlatev Department of Pulmonary Diseases, Hospital of Pulmonary Diseases St. Sofia, Medical University – Sofia
  • Vladimir Milanov Department of Pulmonary Diseases, Hospital of Pulmonary Diseases St. Sofia, Medical University – Sofia
  • Asen Zlatev Department of Pulmonary Diseases Hospital of Pulmonary Diseases St. Sofia Medical University – Sofia

DOI:

https://doi.org/10.7546/CRABS.2022.09.13

Keywords:

lung cancer, smoking, risk factor

Abstract

Smoking as a cause of cancer development has been the subject of research by the International Agency for Research on Cancer (IARC) [1, 2]. The highest rates are for lung (up to 90% of cases), oral cavity (92%) and larynx (87%) cases [3]. Smoking is one of the most important causes in the etiology of lung cancer [3, 4].

The purpose of the study was to determine whether smoking had an effect on the morphological type of lung cancer. One hundred and fifty patients with histologically proven lung cancer by gender, age, smoking experience, and morphology of lung cancer were studied.

The number of men is twice that of women; the highest number of patients is between 40 and 60 years of age. 76.6% of patients are active smokers, 88.6% of them have used cigarettes for more than 10 years, and 59% have smoked more than 20 cigarettes daily. Of the nonsmoking patients, 48.6% are passive smokers.

The distribution by morphological type of lung cancer in smokers indicates that the ratio of squamous type of cancer (59%) is the highest, followed by adenocarcinoma (29.5%), and small cellular cancer (11.3%).

Author Biographies

Iva Popova, Medical Centre St. Kozma and St. Damyan, Bulgaria

Mailing Address:
Medical Centre St. Kozma and St. Damyan
17 Dimitar Manov St
1431 Sofia, Bulgaria

E-mail: iva_popova89@abv.bg

Atanas Zlatev, Department of Pulmonary Diseases, Hospital of Pulmonary Diseases St. Sofia, Medical University – Sofia

Mailing Address:
Department of Pulmonary Diseases,
Hospital of Pulmonary Diseases St. Sofia,
Medical University – Sofia
19 Ivan Geshov Blvd
1431 Sofia, Bulgaria

E-mail: zlatev_1970@abv.bg

Vladimir Milanov, Department of Pulmonary Diseases, Hospital of Pulmonary Diseases St. Sofia, Medical University – Sofia

Mailing Address:
Department of Pulmonary Diseases,
Hospital of Pulmonary Diseases St. Sofia,
Medical University – Sofia
19 Ivan Geshov Blvd
1431 Sofia, Bulgaria

E-mail: vlmilanov@yahoo.com

Asen Zlatev, Department of Pulmonary Diseases Hospital of Pulmonary Diseases St. Sofia Medical University – Sofia

Department of Pulmonary Diseases
Hospital of Pulmonary Diseases St. Sofia
Medical University – Sofia
19 Ivan Geshov Blvd
1431 Sofia, Bulgaria

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Published

30-09-2022

How to Cite

[1]
I. Popova, A. Zlatev, V. Milanov, and A. Zlatev, “The Effect of Smoking on the Morphology of Lung Cancer”, C. R. Acad. Bulg. Sci. , vol. 75, no. 9, pp. 1351–1355, Sep. 2022.

Issue

Section

Medicine